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KMID : 0371320020620040344
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Journal of the Korean Surgical Society
2002 Volume.62 No. 4 p.344 ~ p.347
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Hypokalemic Periodic Paralysis in Graves’ Disease
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Suh Young-Jin
Kim Wook
Chun Chung-Soo
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Abstract
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Thyrotoxic hypokalemic periodic paralysis is a rare endocrine disorder, most
prevalent among Asians, which presents as proximal muscle weakness,
hypokalemia, and with signs of hyperthyroidism from various etiologies. It
is an autosomal dominant disorder characterized by acute and recurrent
episodes of muscle weakness concomitant with a decrease in blood potassium
levels below the reference range, lasting from hours to days, and is often
triggered by physical activity or ingestion of carbohydrates. Although
hypokalemic periodic paralysis is a common complication of hyperthyroidism
among Asian populations, it has never been documented since in Korea. We
report a case of male patient with Graves’ disease accompanied by
hypokalemic periodic paralysis that was treated by total thyroidectomy, and
present a literature review.
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